Gender difference in positive treadmill test and coronary angiogram profile correlation in patient with suspected coronary artery disease at chitwan medical college, Nepal

Background: Tread mill stress test (TMT) is the most commonly performed stress test for diagnosis of coronary artery disease (CAD) in outpatient setting. Tread mill test is often employed for an initial assessment in patients with suspected coronary artery disease serving as a gatekeeper for cardiac catheterization. Methods: We have included all the patients who had tread mill test positive and underwent coronary angiography and subsequently analyzed for the presence of coronary artery disease. TMT test was done using Bruce protocol and results were classified as positive and negative upon ECG changes. Results: Out of 122 participants, 72 (59%) participants were male and 50 (41%) participants were female. Mean age was 63.06±8.78 years and 56.52±9.66 years in male and female group respectively. Smoking (50%) was the number one risk factor in male group and overweight (72%) in female group. The coronary angiogram showed normal coronaries in 36% and 30.5% in female and male participants respectively. Significant coronary artery disease seen in male participants was 61% and in female participants was 54%. The most common coronary artery involved having significant disease during coronary angiogram was LAD 72.7% and 74.1% respectively in male and female group followed by RCA (59.1% and 44.4% ) and LCX ( 31.8% and 22.2%) in male and female participants respectively. Conclusion: There was significant correlation between positive TMT results and coronary angiogram findings in both male and female participants.