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Table of Contents: Volume 17; Issue 11; November 2025

Health Sciences

  1. Sahan, A.G., Aydin, S. and Isik, G.
    ABSTRACT:

    Aim: We all know the different dietary interactions of rheumatological diseases, but we wanted to determine what their effects on patient follow-ups and treatment protocols will be in long-term follow-ups. Introduction: The importance of diet in many different diseases is known and new effects are added every day. Developed societies, although having successfully reduced the burden of infectious disease, constitute an environment where metabolic, cardiovascular, and autoimmune diseases thrive. Patients that have chronic fatigue, joint pain (seasonal variability) and resistant dyspepsia symptoms have food intolerance depended auto immune disease.(FIDAD) Weight loss is frequently offered as a therapy and is aimed at improving some of the components of the metabolic syndrome. Among various diets, ketogenic diets, which are very low in carbohydrates and usually high in fats and/or proteins, have gained in popularity.Similar studies reveal a serious problem of dietary influence, shows that it can.73 of our patients were followed up for sixth years. The patients were evaluated according to their previous and subsequent symptom severity, drug use, and examination results. Material and Method: We included five disease groups in the study. The number of lines followed in the sixth year increased to 73. The symptoms and examination evaluations of the patients were performed. Patients diagnosed with inflammatory bowel diseases (Crohn's disease and ulcerative colitis), multiple sclerosis, psoriatic arthritis, ankylosing spondylitis and reactive arthritis were treated and followed up according to the guidelines, while diet adjustments were made and follow-up was continued. Physical examination and aching joint examination, blood tests and stool analysis were performed every three months. In the follow-up of the patients, the standard treatment protocol was gradually reduced depending on the decrease in the symptoms according to the ACR disease and treatment evaluation criteria. Dietary adjustment was not interrupted in the patients. When an increase in disease activity was observed in reducing the treatment protocol, the previous protocol was returned. Treatment arrangements of the patients were arranged according to EULAR rheumatology criteria. No additions were made to the rheumatological treatment protocols of the patients with the tests performed. According to the results, the treatment protocols of the patients were reduced and discontinued. The follow-ups were continued and the controls were repeated with the same frequency. Patients were instructed to refer again when they felt a change in symptoms or pain.Additional infection treatments were performed in the controls (urinary tract infection, throat infection, etc.). Antibiotic therapy was given when necessary. Result: Nearly all patient treatment aim to collect information on the anniversary of them follow up at years 1 and 2 (year 1 = 40 /73 (54.7%); year 2 = 55/73 (75.3%), with half of the trials requesting intermediate follow- up data at 3 years (70/73 (95.8%). A similar pattern is present between years 3 and 5, with all trials collecting data annually (from year 5 = 70/73 (95.8%); from years 5 to 6 = 71/73 (97.2%) In this way, the rates of no treatment over the years were as observed in the patients who underwent a diet protocol. Discussion: Additional evidence is needed to suggest that diet is the trigger for this remission in patients. However, the fact that diet is a trigger and when it is removed, patients go into remission cannot be ignored. In order to establish a direct connection with these diseases, it must be shown that the defense cells that cause autoimmune disease originate from the same clone. Despite this, it is obvious that a drop of benefit is guiding in the follow-up and treatment of diseases. Although it is certain that more publications and research are needed, it should be considered to be added to medical treatment in cases where adequate treatment response is not obtained or in resistant cases.

  2. Manju V. Raj, Sherin K. and Sherly P. S.
    ABSTRACT:

    Forebrain (prosencephalon), comprising of telencephalon and diencephalon is the anterior part of the brain followed by midbrain (mesencephalon), and hindbrain (rhombencephalon). Telencephalon, the most anterior part involves olfactory bulbs (responsible for sense of smell), olfactory tract, and telencephalic hemispheres (cerebrum) while diencephalon, located between telencephalon and the midbrain involves habenula and hypothalamaus. In this study the telencephalic and diencephalic regions are histologically analyzed in two teleosts, C.auratus and B. striata. In C.auratus, the lateral zone of the area dorsalis, Dl region is highly developed and is the primary visual area. In B.striata, Dm region is highly developed and is involved in the sense of gustation in feeding. The diencephalic region consists of feeding centers like hypothalamus and habenula. Symmetrical habenula is a special feature of surface dwelling visual feeders like Carassius auratus and asymmetrical one isthe feature of bottom dwelling non visual feeders like Botia striata.Hypothalamus, involved in hunger and satiety functions as the main feeding centre of vertebrates by the production ofvarious types of peptide factors responsible for either initiating or ceasing food consumption.

  3. Dr. MOUN-GOSS Noudjoutobaye, Dr. CHIPALO Kabwe, Dr. MAHAMAT Achair Langaba, Pr. ABID Hatim, Pr. ELIDRISSI Mohammed and Pr. ELMRINI Abdelmajid
    ABSTRACT:

    Subtalar dislocation is a rare but serious traumatic injury, frequently complicated by talar necrosis and a consequent poor prognosis. We report a case of an anteromedial talo–naviculo–calcaneal dislocation. Closed reduction was performed in the emergency department under sedation using external maneuvers. Treatment consisted of six weeks of immobilization followed by a structured rehabilitation program. Post-reduction imaging revealed no associated fractures. At the 18-month follow-up, the patient had a stable and pain-free ankle, with no radiological evidence of osteonecrosis.

  4. Houssou Wilfried MILOGNON, Antoine Abel MISSIHOUN, Jonas BOCO, Achille Ephrem ASSOGBADJO and Clément AGBANGLA
    ABSTRACT:

    The present work was undertaken with the aim of evaluating the influence of mineral fertilizers and local varieties on the yield and economic profitability of common bean in order to identify cultivars of the species presenting interesting agronomic potential for fixation and the conversion of atmospheric nitrogen. An experimentation was conducted in Ouèdèmè in the commune of Glazoué (Benin), with tretments including15bean varieties and fertilisation (NPK 14-18-18 and Urea 46% N), applied in a split-plot arrangement. Results showed that production of dry bean seeds depended on the variety and fertiliser used. Variety MSCn3 gave a yield of 2264.925 kg. ha-1with fertilisationused. The unfertilised: 1170.32 Kg. ha-1 versus fertilised plots: 1573.94 Kg.ha-1, a gain of 44%). (unfertilised: 1170.32 Kg .ha-1 versus fertilised plots: 1573.94 kgha-1, a gain of 44%). The analysis of the RVC indicated, however, that the application of fertilisers to common beans was generally less profitable, apart from the local varieties HZZZn3 and GOLn6, whose RVCs were, respectively above 2. At the end of this study, the local cultivars LSCn3, SDCn5 and AOGn1 which gave a small increase in yield in kgha-1 are those which showed a strong increase in leaf biomass. Therefore, subject to further studies, they could be recommended as cultivars predisposed to good fixation and conversion of mineral nitrogen to ammonia.

  5. Flores-Encarnación, M., Jiménez-Flores Y.A., Cabrera-Maldonado C., and Xicohtencatl-Cortes J.
    ABSTRACT:

    The biodegradation of materials that pollute the environment is a topic of research worldwide. Various methods for degrading commonly used polymeric materials such as polystyrene have been documented; however, these methods are often costly or have an unfavorable environmental impact. Polystyrene and its derivatives are used in the manufacture of utensils and food and beverage packaging. Studies have been reported showing the toxic properties of these substances. Biodegradation using microorganisms such as bacteria and fungi has yielded significant results. This paper shows some data related to the ability of the nitrogen-fixing bacterium G. diazotrophicus to biodegrade polystyrene.

  6. Dr. Anurag Telang and Dr. Vilasini Devi Nair
    ABSTRACT:

    Artificial Intelligence (AI) is revolutionising healthcare by enhancing patient care, diagnosis, treatment, and management. This paper explores the diverse applications of AI in health systems, highlighting its potential to improve efficiency, accuracy, and patient outcomes while addressing the associated challenges. AI technologies such as machine learning, natural language processing, and computer vision enable the analysis of vast healthcare data for predictive analytics, personalised medicine, and disease prevention. These tools support clinicians in diagnosing and predicting diseases swiftly and accurately.Applications like virtual health assistants and predictive modelling are fostering more patient-centred care across various healthcare settings. Beyond clinical care, AI is accelerating medical research and drug development by analysing genomic data, identifying biomarkers, and modelling drug interactions, including repurposing existing drugs to address emerging health threats. Despite its promise, AI implementation faces ethical, legal, and data privacy challenges. Ensuring reliability and safety demands ongoing interdisciplinary collaboration, transparency, and rigorous evaluation of AI systems. Addressing these barriers is critical to harnessing AI's full potential and integrating it responsibly into healthcare.

  7. Thaís Rodrigues, Taís Amadio Menegat, Michele Akemi Nishioka, Fabiele Chieregato; Diogo Francisco da Silva de Oliveira; André Eduardo Hilário Amaral; Fábio Alexandre Pinto; José Ricardo de Souza and Patricia Brassolatti
    ABSTRACT:

    Skin rejuvenation is a common procedure in current clinical practice. Various technologies are employed for these therapeutic purposes, with some types of lasers being beneficial due to their safety and low risk of complications. The 1320 nm wavelength is strongly absorbed by water molecules, which produce considerable heating in the skin, contributing to skin rejuvenation. Furthermore, activated charcoal masks can be combined to enhance the desired results. The objective of this study was to evaluate the effects of the black peel procedure on skin rejuvenation, which uses an activated charcoal mask capable of absorbing energy and triggering potential tissue changes. A patient was selected who presented tissue characteristics with the presence of fine and deep wrinkles, enlarged pores, and acne scars. For the evaluation, a comparison of photographs taken before and immediately after the procedure was used, and a 3D camera was used to assess wrinkles and enlarged pores. The results demonstrated that the technique improved skin appearance, particularly in terms of wrinkle reduction and a significant reduction in pore size, with just one application. No adverse events were recorded, and the patient reported comfort and satisfaction with the protocol employed. In conclusion, the non-ablative high-power laser technology, using a wavelength of 1320 nm and the black peel protocol, is safe and provides effective results with just one application.

  8. Zhang Fengfeng
    ABSTRACT:

    As China advances the goals of the Healthy China 2030 Plan, concerns about the physical health of college students persist, with national reports showing only modest gains despite extensive monitoring efforts. This study quantitatively examined the physical health status and related behavioral factors of 291 students from Weifang Nursing Vocational College, using a structured questionnaire to collect data on lifestyle habits, exercise frequency, attitudes toward physical fitness testing, and awareness of health policies. Statistical analysis of the responses confirmed noticeable gaps in students’ fitness levels and highlighted patterns that point to limited engagement with existing health promotion measures. Drawing from these results, the study proposes an integrated physical health promotion model that positions the university, the campus hospital, and the students as interconnected partners in improving wellness. The model emphasizes data-driven strategies in health education, curriculum design, physical activity provision, and exercise-prescription interventions, offering a practical framework for strengthening health outcomes in higher education settings.

  9. Vamougnè Kourouma, Rouguitou Sangbaramou, Mamadi Mariame Camara et Kalil Limbana Diakité
    ABSTRACT:

    La conservation du maïs demeure un enjeu majeur en Guinée, où les pertes post récolte dues à Sitophiluszeamais peuvent dépasser 40 %, compromettant la sécurité alimentaire et la qualité des semences. Les insecticides de synthèse, bien qu’efficaces, posent des risques sanitaires et environnementaux, d’où l’intérêt croissant pour les biopesticides d’origine végétale comme le neem (Azadirachta indica). Cette étude conduite à Faranah avait pour objectif d’évaluer l’efficacité d’extraits de différentes parties du neem a été évaluée dans la protection des grains de maïs. Cinq traitements ont été comparés : un témoin positif (Sarsa-super, T0), les poudres de graines (T1), péricarpe des fruits (T2), feuilles (T3) et écorces (T4), appliquées sur 4 kg de maïs infesté artificiellement par 20 adultes de Sitophilus zeamais. Les observations ont porté sur la pureté, le taux d’infestation, la perte de poids, la mortalité des insectes et le pouvoir germinatif des graines. Les résultats montrent que les extraits de graines (T1) et de péricarpes (T2) ont significativement réduit les infestations (39 %) et les pertes de poids (0,1 %), tout en maintenant une pureté élevée (87 %) et un pouvoir germinatif comparable au témoin (89 %). Les extraits d’écorces (T4) ont été moins performants, probablement en raison d’une faible teneur en métabolites bioactifs. En conclusion, les extraits de neem, notamment ceux issus des grains (T1 et T2), représentent une alternative écologique, économique et durable aux insecticides chimiques pour la gestion post récolte du maïs, contribuant à la réduction des pertes et à la préservation de la qualité semencière.

  10. Dr. Sahithi Sura, Dr. Bhargavi, P., Dr. Ravinder Reddy, K. and Dr. Alekhya, K.
    ABSTRACT:

    Still’s disease, including systemic-onset juvenile idiopathic arthritis (sJIA) and adult-onset Still’s disease (AOSD), is a rare systemic autoinflammatory disorder. It presents with quotidian fever, evanescent salmon-pink rash, arthritis/arthralgia, and systemic manifestations. Case Presentation: We report a 34-year-old woman who presented with prolonged fever, generalised lymphadenopathy, arthralgia, and elevated inflammatory markers. Workup revealed striking hyperferritinemia and elevated cytokines. Bone marrow biopsy showed features suggestive of macrophage activation syndrome (MAS). Diagnosis was established based on Yamaguchi criteria. The patient responded initially to corticosteroids and was later transitioned to biologic therapy. She achieved sustained remission on upadacitinib mono therapy. Conclusion: This case highlights the diagnostic challenges in AOSD presenting as pyrexia of unknown origin (PUO) and the role of targeted immune modulator therapy in refractory disease.

  11. Sumeesha Jaswal, Ajeet Sidana, Shivangi Mehta, Seema Gupta and Gurjit Kaur
    ABSTRACT:

    Background: Recent research highlights the neuroinflammatory basis of Schizophrenia with an intrigue into biomarkers for schizophrenia. The involvement of immunological dysfunction in schizophrenic patients with a blunted type 1 (i.e., IL-2, gamma interferon, IL-12 and TNF-β) and an increased type 2 cytokine pattern (i.e., IL-4, IL-5, IL-6, IL-10 and IL-13) has been seen. Aim: To assess the baseline immunological parameters in drug naïve patients of schizophrenia, compare the levels of interleukins-2,6 and 8 in patients on clozapine and risperidone at baseline, 6 weeks and 12 weeks and study their correlation with clinical response. Material and methods: It was a prospective, randomized, and comparative study. Patients with ICD 11 diagnosis of Schizophrenia were randomized to receive either clozapine or risperidone after baseline assessment of socio- demographic and clinical parameters, baseline blood investigations, immunoglobulins and estimation of interleukin (IL-2, 6 and 8) levels. Levels of interleukins were reassessed at 6 weeks and 12 weeks along with application of PANSS and Glasgow antipsychotic side effect check list. Results: 54 of 65 patients completed the study; 30 patients in clozapine group and 24 in risperidone group. A significant rise was seen in IL-2 levels over 12 weeks. There was decrease in IL-6 levels which correlated with the decrease in positive symptoms at week 12. IL-8 had a negative correlation with the general psychopathology score at week 6 which continued till week 12. Risperidone did not have a significant alteration in the interleukin levels over the 12 weeks. Conclusion: It can be concluded that the elevated cytokine levels (IL-6) at baseline in both clozapine and risperidone groups validate the inflammatory basis of schizophrenia and may be used as the state marker for schizophrenia.

  12. Dr. Mahesh Dave, Dr. Kartavya Nandwana, Dr. Deven kashyap, Dr. Manoj Patidar and Dr. Shrishti Gupta
    ABSTRACT:

    Background: Scrub typhus, also known as bush typhus, is a zoonotic infection caused by Orientia tsutsugamushi, a gram-negative intracellular bacterium transmitted by the larval stage of trombiculid mites (chiggers). It is endemic in the “tsutsugamushi triangle,” including parts of Southeast Asia and India. The disease usually presents with fever, headache, myalgia, lymphadenopathy, and hepatosplenomegaly. However, atypical manifestations involving the renal or prostatic systems are rare, and intra-abdominal abscess formation is an uncommon complication. Case Presentation: A 57-year-old male from Udaipur, Rajasthan, presented with high-grade fever for five days, headache, and diffuse abdominal pain for three days. Clinical examination revealed pallor and mild abdominal tenderness without rash or eschar. Laboratory findings showed anemia (Hb 9 g/dl), thrombocytopenia (52,000/µl), and mildly elevated urea (55.6 mg/dl). Scrub typhus IgM ELISA was positive, while dengue and malaria tests were negative. Abdominal ultrasonography demonstrated a renal abscess (42×29 mm) in the left kidney and multiple prostatic abscesses. Blood and urine cultures were sterile. The patient was treated with intravenous doxycycline (100 mg BD) and azithromycin (500 mg OD) for 10 days, resulting in complete resolution of symptoms and normalization of laboratory parameters. Discussion: Scrub typhus can present with a wide range of clinical manifestations. Although hepatic and renal dysfunction are common, abscess formation in the kidneys or prostate is exceedingly rare. Abscesses may develop due to localized necrosis or secondary bacterial infection. Early imaging and appropriate antibiotic therapy are crucial for diagnosis and management. Conclusion: This case underscores the importance of considering scrub typhus in patients with unexplained febrile illness and intra-abdominal abscesses in endemic regions. Prompt recognition and doxycycline-based therapy can prevent severe complications and improve patient outcomes.

  13. Akitaka Kojima and Naomi Katayama
    ABSTRACT:

    The 2025 edition of the Dietary Reference Intakes for Japanese has raised the recommended vitamin D intake from 5.5 micrograms to 9.0 micrograms. The reason for this is that more and more people are taking measured to protect themselves from the sun on a daily basis, and also to prevent osteoporosis. Therefore, the goal of this study was to develop a new food product (disaster food or space food) using wood ear mushrooms, which are known to be high in vitamin D. First, we began by analyzing how much vitamin D and calcium wood ear mushrooms contain, and we report on this. We requested the Japan Food Research Laboratories, Nagoya branch. To measure the vitamin D and calcium contents of commercially available Chinese wood ear mushrooms and wood ear mushrooms cultivated using commercially available Japanese mushroom beds. As a result, the vitamin D content of commercially available wood ear mushrooms was 83.5 µg/100g, and the calcium content was 108mg/100g. The vitamin D content of cultivated wood ear mushrooms was below the detection limit (0.7 µg/100g or less), and the calcium content was 49.5mg/100g. Vitamin D is not only required to be taken together with calcium to prevent osteoporosis, but is also an important nutrient because it regulates immune function, inhibits cell proliferation and differentiation, and suppresses inflammation. However, this analysis has revealed that the foods we eat, thinking we are getting vitamin D, may actually contain no vitamin D or only trace amounts. In the development of future disaster and space food, it is necessary to clarify the nutritional analysis values of the wood ear mushrooms to be used before processing them into food.

  14. Oluwakemi Iyabo Adeniji, Adetunji Oladeni Adeniji and Anuoluwapo Oluwapelumi
    ABSTRACT:

    Introduction: Drug Revolving Fund (DRF) is a scheme whereby drugs and medical consumables are sold at an affordable cost (addition of the cost price plus a mark-up) to generate revenue which is used to replenish stocks, The implementation of the DRF scheme ata maximum capacity, promotes accessibility, availability, affordability, and sustainability of quality drugs and medical consumables. However, there has been reports on knowledge and certain factors towards the effectiveness of the DRF scheme. This study was therefore conducted to determine knowledge and factors influencing drug revolving fund scheme among clients attending selected hospitals in Ijebu Ode, Ogun State, Nigeria. Methodology: Cross sectional descriptive research design was used for the study. The study population were clients attending selected hospitals in Ijebu Ode. A formula was used to calculate the sample size, arriving at 132 respondents. Multistage sampling technique was used to select respondents for the study. Experts validated, structured questionnaires, with each divided into five sections were used to collect data. Analysis of the generated data was done using Statistical Package for Social Sciences (SPSS) version 25.0 and the results were presented using descriptive statistics. Results: The study revealed a mean age of 37±1. Findings shows that clients attending selected hospitals at Ijebu-Ode Ogun State have good knowledge 79(59.8%) of the DRF scheme. However, it was discovered that some factors inhibit the utilization of DRF scheme among patients as most of them113 (85.6%) affirmed that there is ineffective system of drug administration and control. Conclusion and Recommendation: Based on the results of this study, it was concluded that despite good knowledge of the DRF scheme, some factors militate against effectiveness of the scheme among patients attending selected hospitals in Ijebu Ode, Ogun State, Nigeria. The study recommended that, the Government should subsidize essential drugs to improve patients’ access and prevent over charge in drug prices and that health workers should ensure regular and adequate procurement of essential drugs in the health facility.

  15. Mamadi Mariame CAMARA, Paul Windinpsidi SAVADOGO and Lanciné SANGARE
    ABSTRACT:

    Polyphenol oxidases (PPOs) are enzymes involved in the oxidation of polyphenols into quinones under the action of molecular oxygen, causing certain vegetables to brown. They also participate in essential biological processes such as cellular respiration, photosynthesis, and plant defense systems. Faced with agricultural challenges, including the proliferation of pests, the harmful effects of chemical inputs on the production chain, and the short shelf life of eggplants, the search for sustainable solutions is intensifying. This study aims to evaluate the impact of combining castor meal and castor oil on improving the nutritional and enzymatic properties of eggplants. The experiment was conducted using a randomized block design (4x4), with four treatments: a negative control, the application of cake (1.9 t/ha), castor oil (5 l/ha), and a combination of the two (0.95 t/ha + 2.5 l/ha). Analysis of the results reveals that the fiber content of the fruit reached 7.45% for the control, followed by 7.02% for castor oil, and 6.68% and 6.85% for oil alone and the meal-oil combination, respectively. In terms of protein, castor meal achieved 21.26%, compared to 17.55% for castor oil, while the meal-oil mixture and the negative control showed 13.30% and 0.18% respectively. In terms of enzyme activity, castor oil induced peroxidase of 15.18 IU, while the other treatments showed values of 11.95 IU (control), 10.96 IU (cake-oil) and 10.15 IU (cake alone). The polyphenol oxidase rate was slightly higher in the control (12.15 IU) and lower with the meal-castor oil combination (11.97 IU). The integration of meal and castor oil into eggplant cultivation is therefore an innovative approach to optimizing the nutritional value of the fruit while enhancing peroxidase activity and reducing polyphenol oxidase activity.

  16. Mr. Lingaraju, C.M., Mrs. Ashwini, C. and Mrs. Elizabeth Lizi
    ABSTRACT:

    Anemia is a condition where your blood doesn't have enough healthy red blood cells or hemoglobin, leading to a reduced ability to carry oxygen to your body's tissues. This can cause symptoms like fatigue, weakness, and shortness of breath.The majority of anaemia in India is categorized as mild or moderate with under 3% of women and children being reported as severely anemic. However even mild and moderate anemia if left untreated can lead to serious long term health consequences. Despite several efforts by the Government of India, the national burden of anaemia remains high and its growing prevalence is concerning to India’s public health system. Objectives: Objectives is to Asses the knowledge and perception of anemia among rural elderly at Mysuru Methods: The research design selected for this study was descriptive design. cross sections of the population under Varuna health and wellness center .the total sample size was 60 rural Elderly at Varuna, Mysuru. Result: Result revealed that majority of Rural elderly are have anemia there is association between the knowledge and perception of Anemia with the selected variable such as gender, education and also income. Conclusion: It was concluded that the rural Elderly having high prevalence rate of Anemia and there is statistical significance association between The knowledge and perception with the demographic variable such as gender and education and income.

  17. Dr. Shilpa, Dr. Narayan Walavalkar, Dr. Hemalatha, Dr. Prajwal Hadli and Dr. Patil, M.B.
    ABSTRACT:

    Peri-implant soft tissue management is a critical determinant of long-term dental implant success, influencing esthetics, biological stability, and patient comfort. While early implantology prioritized osseointegration, contemporary evidence emphasizes the importance of keratinized mucosa width, mucosal thickness, and soft tissue contour in preventing inflammation, marginal bone loss, and mucosal recession. Autogenous grafts such as free gingival grafts (FGG) and subepithelial connective tissue grafts (SCTG) remain the gold standard for soft tissue augmentation, whereas acellular dermal matrices, collagen scaffolds, and platelet-rich fibrin (PRF) provide effective alternatives with reduced morbidity. Proper surgical technique, including meticulous flap design, vascular preservation, and biologically guided prosthetic planning, is essential for maintaining peri-implant tissue health. Digital technologies, minimally invasive approaches, and phenotype-based planning further enhance esthetic and functional outcomes. Integrating these strategies ensures predictable long-term stability, optimal esthetic results, and improved patient satisfaction, highlighting soft tissue management as a cornerstone of modern implant therapy.

  18. Dr. Vaibhav Vijaya Ravindra Mahajan and Dr. Aarti Gorakhnath Kanchar
    ABSTRACT:

    Background: Acne vulgaris is a common inflammatory disorder of the pilosebaceous unit with multifactorial etiology. Conventional management typically includes topical retinoids, antibiotics, and hormonal therapy, yet recurrence and adverse effects remain major concerns. Homoeopathy offers individualized prescription based on symptom totality and constitutional characteristics, aiming at internal hormonal and immunological balance. Objective: To evaluate the clinical effectiveness of individualized Homoeopathic treatment in patients with acne vulgaris using standardized severity scoring and patient-reported outcomes. Methods: This prospective observational study was conducted over 12 weeks and included 40 patients diagnosed with acne vulgaris. Remedy selection was based on individualized totality, miasmatic background, and repertorial correlation. The Global Acne Grading System (GAGS) and Dermatology Life Quality Index (DLQI) were used for assessment at baseline, 6 weeks, and 12 weeks. Results: A statistically significant reduction in GAGS and DLQI scores was observed. Mean GAGS decreased from 21.8 ± 4.2 at baseline to 12.4 ± 3.1 at week 12 (p< 0.01). Marked improvement occurred in inflammatory lesions and seborrhea. Frequently prescribed remedies included Pulsatilla, Heparsulphuris, Sulphur, Natrum muriaticum, and Kali bromatum. Conclusion: Individualized Homoeopathic treatment demonstrated beneficial clinical outcomes in acne vulgaris without any adverse effects. Larger controlled studies are recommended to further validate these findings.

Social Sciences and Humanities

  1. Pavithra, P., Jahitha Begum, A., Ponnusamy, P. and Ponselvakumar, G.
    ABSTRACT:

    Artificial Intelligence Chatbots have become cutting-edge technologies for language learning, providing personalized and interactive experiences for students. Specifically in English oral proficiency, AI chatbots offer opportunities for improved speaking practice, feedback, and language acquisition. Objective: This study investigates undergraduate students’ perceptions of AI chatbots’ abilities to improve English oral proficiency among non-English majors. Method: A sample of 230 undergraduate students of non-English majors was selected. The research employedsurvey method,utilizing questionnaire. Findings: The quantitative analysis revealed that 71.9% of participants viewed learning effectiveness and language fluency as being strongly and positively correlated (r = .719), indicating that improvements in fluency coincide with enhanced learning outcomes; 82.7% demonstrated a very strong positive correlation between learning effectiveness and usability of AI Chatbots (r = .827), emphasizing how crucial user-friendly interfaces are to maximizing educational opportunities. Most participants agreed that AI chatbots are useful for language acquisition. However, they identified several areas for improvement such as addressing feelings of nervousness, enhancing control over the learning process, and diversifying conversation topics to increase enjoyment and effectiveness. Novelty: Despite significant progress in AI technology, there remains a considerable lack of research on learners’ views about using AI chatbots to improve their English speaking skills. Moreover, few investigations have assessed the influence of communication facilitated by chatbots on developing linguistic competence. The study’s findings show that AI chatbots have enormous potential in improving English oral proficiency among undergraduate students.

  2. Fatima Ezzahra Bousselham, FTOUH El Mostafa, ABYRE Asmaa and KERBACH Mouna
    ABSTRACT:

    Les partenariats public-privé (PPP) constituent un levier stratégique du développement territorial et touristique, en réunissant acteurs publics et privés autour de projets communs. Toutefois, la diversité des logiques institutionnelles et la répartition inégale de l’information entre partenaires peuvent engendrer des asymétries d’information, sources de malentendus, de tensions et de déséquilibres communicationnels. Ces fragilités internes risquent de compromettre la cohérence du discours collectif et, par conséquent, de fragiliser l’image de marque touristique du territoire. Cette recherche vise à évaluer dans quelle mesure la communication territoriale parvient à réguler ces déséquilibres informationnels et à favoriser la cohérence des messages diffusés par les acteurs publics et privés. En s’appuyant sur une approche qualitative menée auprès des principaux acteurs de la gouvernance touristique de la région Béni Mellal-Khénifra, elle cherche à comprendre comment la qualité du dialogue partenarial influence la construction et la crédibilité de l’image territoriale. Les résultats permettront d’identifier les nœuds critiques de la communication au sein des PPP et d’envisager des leviers pour renforcer la performance et l’attractivité territoriale.

  3. SAWADOGO Honorine Pegdwendé
    ABSTRACT:

    L’aumône faite aux mendiants est une vielle pratique observée dans toutes les sociétés à travers le monde. Cette pratique est également observée dans les rues de la ville de Ouagadougou. Les carrefours des avenues, la devanture des mosquées, des églises, les parking des établissements bancaires et des épiceries, les stations d’essence, etc., sont des lieux privilégiés par les mendiants. L’objectif de cette étude est d’examiner la capacité de l’aumône à relever la personne mendiante. À travers la théorie de l’interactionnisme, une approche qualitative a été adoptée pour observer les interactions entre les différents acteurs qui interviennent dans le circuit de l’aumône. Trois types de matériaux ont été combinés, à savoir, l’entretien approfondi semi-directif, l’observation directe, et les sources documentaires. Le travail de terrain a permis d’échanger avec trente-huit (38) personnes : 17 personnes mendiantes, 7 marabouts/maîtres coraniques, 3 leaders religieux et 11 citadins pris au hasard. Les entretiens réalisés ont été littéralement transcrits et analysés suivant la technique d’analyse de contenu. Les résultats mettent en exergue d’abord les pratiques et représentations socioculturelles de l’aumône faite aux mendiants. Il ressort que l’aumône est perçue à la fois comme une obligation religieuse, une forme de protection sociale, un geste de solidarité rapprochant riches et pauvres à travers la redistribution des richesses. Ensuite, le deuxième résultat souligne le marché de l’aumône qui, comme tout marché, dévoilent les acteurs qui nourrissent le système : les donateurs qui échangent les biens matériels (en espèce ou en nature) contre des biens immatériels (grâces, bénédictions, santé, protection). Derrière le donateur et le mendiant, il y a les leaders religieux, les marabouts et voyants qui encouragent ou prescrivent des sacrifices intégrant l’aumône aux mendiants. Enfin, le troisième résultat relève que l’aumône n’est qu’un cercle vicieux de la misère au regard des revenus de la mendicité qui sont précaires et aléatoires et donc  une activité qui ne pourrait enrichir celui qui s’y emploie.

  4. KOFFI Lopez Emmanuel Oscar
    ABSTRACT:

    Associé au pouvoir et à la violence, l’autorité est un concept qui mérite d’être examiné. Pour Arendt (1972, p. 123), elle ne relève ni de la contrainte ni de la persuasion ; elle repose sur une forme de reconnaissance qui s’inscrit dans une continuité historique. Les Temps Modernes sont marqués par un processus de désacralisation des sources traditionnelles de la relation de commandement à obéissance entraînant une crise de ses formes d’exercice. Cette contribution se situe dans le cadre théorique de la philosophie de l’éducation et se propose d’interroger les conditions d’une autorité légitime. Il sera question d’analyser les facteurs ayant conduit à son érosion dans les sociétés modernes pour mieux entrevoir des pistes de solutions. Cette étude en mobilisant la méthode analytique, vise à comprendre les dynamiques qui relient la crise de la prééminence à des phénomènes comme la montée des incivilités, la défiance des institutions. L’objectif est de réfléchir aux modalités de préservation des hiérarchies pour le bon fonctionnement et la cohésion de la collectivité.

  5. TAPSOBA Kader and Dr. Patrice KOURAOGO
    ABSTRACT:

    Cette étude porte sur les enjeux et défis de l’appropriation des médias sociaux par les entreprises publiques au Burkina Faso. Elle met l’accent sur l’intégration des éléments culturels locaux dans la communication numérique comme facteur d’efficacité, de proximité et de performance organisationnelle. Dans un contexte marqué par la pluralité linguistique et symbolique, les entreprises publiques doivent adapter leurs stratégies de communication à la diversité culturelle de leurs usagers afin d’assurer la légitimité et la portée de leurs messages. L’article a pour objectif d’analyser les enjeux et les effets de l’intégration des éléments culturels locaux dans l’appropriation des médias sociaux par les entreprises publiques du Burkina Faso. La question de recherche s’interroge sur comment l’intégration des éléments culturels locaux dans la communication numérique peut contribuer à améliorer la performance et la légitimité des entreprises publiques au Burkina Faso avec une méthode mixte à dominante, structurée autour d’entretiens semi-directifs, de l’analyse de contenu et de la triangulation des sources. Il ressort quel’appropriation des référents culturels dans les campagnes numériques est encore limitée. La plupart des entreprises publiques ont une faible intégration des éléments culturels dans leur communication numérique.L’étude révèle cependant une prise de conscience progressive de l’importance de l’adaptation culturelle comme levier d’engagement citoyen, de cohésion symbolique et d’amélioration de la performance organisationnelle. Elle plaide pour une stratégie nationale de communication publique interculturelle, fondée sur l’usage des langues nationales, la valorisation des identités locales et la co-construction des contenus numériques avec les communautés.

  6. Nwafor-Orizu Onyinye, N.
    ABSTRACT:

    The capital market plays a crucial role in stimulating economic growth and development in a country. Its role in maintaining financial stability through trading in the primary and secondary markets earns it a prized position as one of the most effective ways of transforming a country’s economy, boosting investors’ confidence and preserving the integrity of the capital market. Fostering a safe and reliable market requires a sound regulatory and supervisory regime as well as a strong enforcement mechanism capable of maintaining effective dispute resolution. The inherent nature of the market necessitates the ability to effectively and efficiently resolve disputes as they arise, thereby enhancing the market’s effectiveness in fostering economic growth and development. The judiciary plays a key role in the adjudication of capital market disputes. The paper analyses the pertinent issues that arise in the adjudication of capital market disputes, including jurisdictional conflict between the Federal High Court and the Investments and Securities Tribunal, slow and cumbersome judicial processes due to insufficient expertise of judicial officers to decide on intricate capital market cases, and incessant interlocutory applications by litigants, amongst others. The paper asserts that strengthening the judiciary to create a strong and efficient dispute resolution body with clear, unambiguous jurisdictional boundaries, improved capacity-building knowledge, enhanced enforcement tools and the establishment of a sanction regime for unnecessary applications by litigants is essential for a resilient and effective Nigerian capital market.

  7. Dr. Santoshi, G.
    ABSTRACT:

    IPOs are emerging as a major significance to the economy in a global dynamic environment. They are playing a vital role in each and every sectorand resulting in contributing to the growth of the economy. In this context, present study has taken top 4 emerging sectors which Includes, Information Technology, Healthcare, E-Commerce & Fast Moving Consumer Goods. The selected sectorial performances are evaluatedby the 2 analytical tools i.e. return on investment (ROI) and market capitalisation (MC). The study made use of secondary data, such as webpages and journal papers.Since 2007, 25 companies in IT sector went to SME IPOs, 24 companies in Healthcare sector went to SME IPOs, 6 in E-Commerce & 26 in FMCG sector. From the analysis by taking 2 parameters i.e. return on investment and market capitalisation, it was concluded that IT industry is performing well in comparison to other 3 emerging sectors.

  8. Amin El Sayed Ahmed Lotfy
    ABSTRACT:

    Purpose and Design: This research develops an empirical accounting and legislative framework for integrated financial, tax, and sustainability disclosure to enhance Egypt’s economic competitiveness, governance, and alignment with global best practices. It is designed as an applied comparative study combining legal, accounting, and institutional perspectives. Method and Approach A mixed-methods approach was employed, including: • Content analysis of Egyptian laws and accounting regulations related to financial, tax, and ESG reporting. • Comparative analysis of successful disclosure frameworks in developed countries, particularly the EU’s CSRD and South Korea’s DART system. • Empirical data collection through surveys and expert interviews with 204 respondents from Egyptian enterprises and regulatory bodies. Findings: The study reveals significant fragmentation and inefficiencies in Egypt’s current financial, tax, and ESG disclosure landscape, leading to legal uncertainty and high compliance costs. Results demonstrate that adopting an integrated accounting and legislative framework, supported by a unified digital platform, can significantly enhance: • Transparency and investor confidence. • Access to sustainable finance. • Alignment with global sustainability standards. A draft legislative proposal is presented, detailing articles, institutional roles, penalties, and phased implementation strategies. Originality and Value: This research represents one of the first comprehensive accounting and legislative frameworks for integrated disclosure in the Egyptian context. It bridges theoretical models with practical regulatory reforms, providing empirical evidence and a legislative blueprint applicable to other emerging economies. Theoretical, Practical, and Social Implications • Theoretically: enriches stakeholder theory, legitimacy theory, and institutional theory within disclosure regulation. • Practically: offers policymakers and accountants a roadmap to modernize Egypt’s disclosure framework. • Socially: promotes trust, transparency, and sustainable development in line with Vision 2030.

  9. Dr. Bandameedi Nagaraju
    ABSTRACT:

    This study examines how evolving monetary policy mechanisms and the proliferating use of digital payments have affected economic outcomes in India from 2020 to 2025. While the central bank’s traditional instruments repo rate, reverse repo rate, liquidity management—remain pivotal, digital innovation has emerged as a major catalyst for refining monetary policy transmission. By analysing GDP growth, lending rates, inflation behaviour, and payment system modernization, the paper uncovers links between policy stance and economic momentum. Panel regression and ARDL methodologies reveal that integration of digital payments leads to improved transmission efficiency, lower lending rates, and enhanced macroeconomic stability. The findings suggest that policy makers should leverage digital financial infrastructure for more responsive and inclusive monetary policy, ensuring resilience in the face of domestic shocks and global volatility.

  10. Rahila
    ABSTRACT:

    This paper explores a comparative study of John Milton and Mirza Ghalib, two poetic giants who, despite belonging to distinct linguistic and cultural traditions, share a common spirit of rebellion and introspection. Through a close reading of Paradise Lost, Paradise Regained, and Deewan-e-Ghalib, this study investigates how both poets question divine authority, confront moral contradictions, and reinterpret religious dogma in light of human experience. While Milton’s Puritan worldview seeks to justify divine justice through reason and scripture, Ghalib’s Urdu poetry expresses an existential skepticism toward the same cosmic order. The analysis reveals how both poets transform theological discourse into a humanistic quest for freedom, positioning poetry as a dialogue between the finite and the infinite. The topic Comparative Literature in itself offers a broader range of research to a student who is willing to dig deep the intertextuality of literature. The comparisons more often lead to a new dimension of thought, explore hidden meaning and most importantly flourish the life in a text. As in the words of Julia Kristeva, “Any text is the absorption and transformation of another.” So, we can say literature is a process of dialogues and counter dialogue or a continuous reply of reply to the text. The stalwart of English literature of the Puritan age, John Milton (1608-1674), famously known for his masterpiece, ‘Paradise Lost’ and the Urdu literature poet Mirza Ghalib (1794-1869), both share the same kind of magnitude. When we study both the poets the grandeur, the diction, the style, the tone these poets have some magnificent impact on readers. In spite of having linguistic differences, cultural differences, religious differences their ideas are equivocally radical, phenomenal. It is not just an overnight conclusion but over the passing decades people looked upon their works and found it still majestic and stately. In the age of globalization when we study these writers closely we realize that humanity has just one race and that is humanity itself. We cannot make an analogy between the writers that how they appear same but on some context they almost react the same towards the society. In the case of John Milton when Europe was loaded with Puritan thoughts he dare to project the religious mythology in his own way, though we cannot fully understand the intention of the writer what he means by his text, the collective response was to him was a little different as William Blake argued that “he was of the Devil’s Party without knowing it. The radical views of John Milton is very much similar to Mirza Ghalib. Milton and Ghalib both belong to the same school of thought who ponder over the development of mankind. They both carry the responsibility of more a moral teacher. We can perceive the same pinch in Ghalib’s poetry, as he says, Humko Maloom hai Jannat ki Haqeeqat lekin Dil ke Khush Rakhne ko Ghalib yeh Khayal Achha hai… How Mirza Asadullah Khan Ghalib satirizes over the concept of heaven and even indirectly makes fun of it. The spirit of questioning over the Lordly sayings is as bitter as we find in Milton’s.

  11. Nombamba OUEDA, Mondombalouki TCHALLA, Ibrahim TCHAKALA and Moctar Limam BAWA
    ABSTRACT:

    Les zones de dépression constituent des réservoirs d’eaux usées et également des dépotoirs de déchets de différentes natures ; sont alors de potentielles sources de pollution des eaux souterraines. L’objectif de notre étude est d’évaluer le risque sanitaire de la zone de dépression d’Amadahomé. Ainsi, une enquête est réalisée pour recueillir les vécus de la population sur les pratiques sanitaires et d’assainissement. Des analyses bactériologiques et physico-chimiques ont été effectuées selon les normes de l’Association Française de Normalisation sur des échantillons d’eau de forages. Les résultats ont montré que 90% des répondants utilisaient l’eau de forage pour la consommation, 76% déclaraient ne pas être satisfaits de la qualité de ces eaux et seulement 10% des ménages faisaient recours au traitement des eaux. Une proportion importante de ménages allant à 68% témoignaient avoir vécu les inondations, confirmant donc la vulnérabilité de la zone. Quant aux résultats des analyses bactériologiques, il ressort que la flore aérobie mésophile est présente dans tous les échantillons avec une forte présence dans l’échantillon EF1 à hauteur de 12000 UFC/mL. Les paramètres physico-chimiques révèlent que la majorité des eaux analysées ont un caractère acide surtout l’eau du forage EF6. La conductivité est remarquable dans deux forages notamment EF4 et EF6 avec des valeurs respectives de 1398 et 983 µS/cm, traduisant ainsi une forte charge minérale. La présence des ions nitrates est considérable dans EF4 et EF6 à de concentrations égales à 152 et 99,77 mg/L respectivement ; elle peut être source d’une pollution organique.

  12. Inam Khan
    ABSTRACT:

    Work Stress is a challenge for banking industry as it can negatively affect job performance of employees. Work Stress may impair their ability to concentrate, make decisions, and handle complex tasks employees experience high levels of stress. This can lead to a decline in their productivity and job performance. When employees feel burned out, they may be more likely to take sick leave or seek employment elsewhere, impacting the continuity and stability of the workforce. High levels of work stress can contribute to increased absenteeism and higher turnover rates among employees. Banks rely heavily on providing quality customer service. The results of correlations and regression analysis revealed that there is negative correlations between work stress and job performance of the employees. Work stress is higher in private banks than in government banks. There was negative impact of work stress on job performance. If employees are stressed, they may become less patient, less empathetic, and less willing to go the extra mile to assist customers. This can have a negative impact on customer satisfaction and loyalty. Therefore, it is important to minimise the impact of work stress on the job performance of employees through proper training and development and maintaing the conducive working environment in public and private sector banks.

  13. Mohamed Abdulkadir Roble
    ABSTRACT:

    This study investigates the relationship between transformational leadership, organizational support, work environment, and remote worker performance within Somalia's banking sector. Using the Job Demands-Resources (JD-R) framework, the research explores the direct effects of these constructs on the performance of Remote Workers. Data were collected from 355 respondents and analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM). The results reveal significant positive relationships between transformational leadership and organizational support and the work environment, emphasizing the role of leadership in fostering supportive organizational climates. Furthermore, organizational support and the work environment significantly enhanced remote worker performance, highlighting their importance as critical job resources. By expanding the JD-R framework, this study contributes to the theoretical understanding of leadership and organizational dynamics in remote work settings. It offers practical recommendations for optimizing remote worker performance in developing economies. These findings hold important implications for organizations seeking to adapt to the challenges of digital transformation and remote work in similarly resource-constrained contexts.

  14. Amy Felicia Danielle and Prof. Irene Lalruatkimi
    ABSTRACT:

    Digital platforms have emerged as powerful tools for governance. Mizoram, situated in the Northeastern region of India bordering Myanmar and Bangladesh comprise of strong oral traditions and community-based political practices, this transition marks a significant paradigm shift in how political discourse is constructed, framed and disseminated. This study explores the evolving nature of political communication through a focused content analysis of social media handles managed by the state government. The research investigates how state agencies, particularly the Information, Public Relations, Printing and Stationery Department and the Chief Minister’s official social media accounts, employ social media platforms to shape public opinion, promote policy narratives and engage citizens. Using qualitative content analysis approach, the study categorises based on tone, message type, visual symbolism and thematic framing across key governance areas such as development, identity politics, crisis response and cultural representation. Grounded in the theories of Habermas’s public sphere theory and platformisation theory, the study critically examines how digital communication alters traditional participatory structures. The shift from grassroots oral discourse to centralized, curated messaging that often blends bureaucratic efficiency with cultural symbolism tailored to resonate with Mizo identity. While this has improved accessibility and visibility of political content, the study also uncovers gaps particularly in inclusivity, digital literacy and the marginalization of rural voices in the digital public sphere. Citizen’s response patterns reflected to comments, shares and discourse tone on social media reveal evolving expectations around transparency, accountability and representation. The study recommends a culturally contextualized and inclusive digital strategy for political communication in Mizoram. By aligning technological advancement with local traditions, linguistic diversity and community norms with government agencies can be more effectively engage with the public to foster trust and strengthen democratic participation. The study contributes to the broader understanding of how regional governments in culturally complex societies can adapt digital tools for democratic renewal without compromising traditional values.

  15. Kshitiz Upadhyay-Dhungel
    ABSTRACT:

    This paper explores Kalkiism as a modern reinterpretation of Hindu eschatological theology rooted in the myth of Kalki, the final avatar of Vishnu. While traditional Hindu cosmology presents Kalki as a future divine warrior who will end the Kali-Yugas and restore dharma, Kalkiism reimagines this figure as a symbolic and philosophical response to contemporary global crises. Drawing on ancient scriptures such as the BhagavataPurana, Mahabharata, and Kalki Purana, the article outlines the moral, ecological, and societal decline characterizing Kali-Yugas and the conditions prophesied for Kalki’s emergence. The study proposes Kalkiism not as a rigid religious doctrine but as an evolving ethical movement emphasizing accountability, environmental justice, spiritual militancy, and collective moral awakening. It also critiques the political co-optation of Kalki imagery and addresses challenges in coherence and interpretation. Ultimately, Kalkiism offers a hybrid framework that blends myth, ethics, and activism to inspire transformative change in an age of systemic collapse. This academic paper also presents:belief in the Consequences of Human Action, Restoration of Dharma, Apocalyptic Ethics, Technological and Environmental Critique, Collective Messiahship, Accountability and Responsible Humanity as seven Key Tenets of Kalkiism.

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EDITORIAL BOARD

MIEZAN Essou Koffi Benjamin
Côte d’Ivoire
Dr. Govindaiah Simuni
USA
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran