Evaluation of follicle stimulating hormone, testosteron and factors responsible for male infertility in khartoum-sudan

Background: Gonadotropin (FSH) and testosterone abnormalities are usually associated with abnormal spermatogenesis. Aim: This study aimed to evaluate Follicle stimulating hormone and Testosterone among Sudanese infertile population. Methods and Materials: The frequent descriptive cross-sectional study was conducted during the period from October 2014 to March 2015 in which a total of ninety infertile men all over three years of infertile condition and ten age-matched controls with proven fertility were selected for the study. Follicle stimulating hormone (FSH) and testosterone levels were estimated by fully automated AIA 360 (TOSOH) using the manufacturer kits. The participants' semen sample were collected and proceeded according to WHO manual guidelines. The data and the hormonal results were analyzed using SPSS version 16. Results: A hundred participants volunteered in this study, ten of them were fertile and ninety were infertile. All of the participants fall into age ranged from (25-60 years). Out of 90 infertile males, 69(76.7%) were azospermic and 21(23.3%) were oligospermic. In comparing FSH and Testosterone levels of infertile and fertile group, it's appear that there is a significant statistical relationship (P value = 0.000). When comparing the means of FSH, and Testosterone regarding infertile subgroups of azospermia and oligospermia it found that there was statistical significant relationship of Testosterone hormone (P value = 0.01), unlike FSH hormone which revealed insignificant relation (P value 0.54) Conclusion: Elevation levels of gonadotropin (FSH) hormone and decreasing levels of Testosterone hormone will directly affect the spermatogensis process leading to condition known as infertility.