CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Antithyroid peroxidase antibody and extractable nuclear antigen antibody in celiac disease-A preliminary communication

Author: 
Dr. Usha, Dr. Deepa Rani, Dr. Neha Chaurasia, Dr. O. P. Mishra, Dr. Andleeb Zehra and Dr. Agrawal, N. K.
Subject Area: 
Life Sciences
Abstract: 

Celiac disease is very common in our place. Aim was to find out prevalence of various autoantibodies in CD. Material and method: Total 22 cases of celiac disease along with 50 healthy cases were studied within a period of 6 months. Anti tissue transglutaminase (Ttg), anti thyroid peroxidase (TPO), Anti nuclear antibodies (ANA) were done by ELISA method, while antibody to extractable nuclear antigen (ENA), (Sm,RNP,SSA,SSB,Scl70,Jo-1,centromere) and antigliadin antibody were done by dot blot method. Result: Males (59.09%) were more affected than females (40.92%).In males disease was mostly seen between 1.5 to 15 years (76.92%) while in females disease was found in 15 to 30 years (77.77%). Chronic diarrhoea was the most common manifestation (68.18%), followed by failure to thrive (31.81%), pain in abdomen, nausea vomiting (22.72%),fullness of abdomen, belching (18.18%)and loss of appetite (13.63%). One case was associated with Type 1 Diabetes mellitus (TIDM) while in 3 cases patient had Type 2 Diabetes mellitus. About 11 cases (50%) had some kind of autoantibodies. Commonest was anti TPO antibodies detected in 27.27% cases followed by ANA and centromere Ab (9.09%), anti smith (Sm) Ab and anti scleroderma 70 and anti Jo-1 antibody (4.54%) each. Clinically only 3 patients had symptoms of hypothyroid. None of the patient positive for anti centromere antibody had feature of scleroderma. One patient positive for both anti Jo-1 and Scl 70 had muscle weakness. Two patients were positive for ANA out of which one was positive for anti Sm Ab also but clinically no evidence of SLE was present. Antigliadin Ab detected by dot blot method in 68.18% cases. Thus our study concludes that celiac disease in 50%cases is associated with some kind of antibodies of hypothyroidism, scleroderma, SLE or polymyositis, but clinically hypothyroidism is more common.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran