Comparison between anti-diabetic effect of ethanolic extract of Hibiscus Rosa Sinensis leaves and flowers in diabetic rats

Diabetes continues to cause a great economic loss every year. With commercially available synthetic drugs having serious adverse events, traditional source of drugs like plants continue to play a significant role in search for a safer and effective treatment. In this study, the antidiabetic effect of ethanolic extract of leaves and flowers of Hibiscus Rosa Sinensis (HRS) are compared along with a standard drug, metformin. Diabetes was induced using Alloxan in Wistar Albino Male rats and were divided into 4 group respectively. Rats were treated separately with the extracts and standard drug with blood glucose monitoring at regular intervals for 21 days. Ethanolic extract of flowers is more effective then ethanolic extract of leaves with neither of them developing hypoglycemia which was observed with metformin treatment.