Coronavirus infection in children during a pandemic. review

The generalized data of publications on coronavirus infection in children, including neonatal and subsequent age periods, are presented in the review. Children are less likely to get sick than adults, but they are more often asymptomatic carriers of infection. The similarities and differences in the course of infection in adults and children are shown. A rarer incidence and a mild course of infection can be associated with the peculiarities of the activity of the immune system in children due to frequent age-related vaccinations and more frequent "contact infections". In addition, the difference in the expression sites of the APF2 receptor may play a role, facilitating the penetration of the pathogen of CoV-19 into the cell (in children - in the intestine, in adults - in the respiratory tract). Children develop gastrointestinal tract pathology more often than adults when infected with SARS CoV-2, typical and atypical manifestations of Kawasaki disease are found. The main recommendations of the Ministry of Health of the Russian Federation on the treatment and prevention of coronavirus infection are presented.