In vitro antibacterial activity of methanol extract from the leaves of Wedilia trilobata and Emilia sonchifolia against pathogenic bacteria

Now a day, a search is going on for new antimicrobial agents due to the negative effects of existing antibiotics and the constant development of bacterial resistance. This study assessed the phyto chemical screening and antibacterial activities of methanol extract from the leaves of Wedilia trilobata and Emilia sonchifolia. Methanol extract from the leaves of Wedilia trilobata and Emilia sonchifoliahas an antimicrobial activities against 5 bacteria K. pneumoniae, E. coli, E. faecalis, S. aureus and P. Aeruginosa and it was investigated using a disc diffusion and minimum inhibitory concentration assay (MIC). Both disc diffusion and (MIC) of the extracts ranged from 5 to 20 µg/m. Results of phyto chemical screening of methanol extracts of W. trilobata and E. sonchifolia showed the presence of tannins, flavonoids, terpenoids, alkaloid, poly phenols, saponins and cardiac glycosides absent. The total content of flavonoids and poly phenols in the methanol extracts of the studied species positively correlated with their antioxidant properties .The study findings indicate that bioactive natural products from these plants may be isolated for further testing as leads in the development of new pharmaceuticals in food preservation as well as natural plant-based medicine.