CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Prevalence of hypothyroidism in a hospital based sample of pregnant kashmiri women with recurrent abortions and pregnancy outcome

Author: 
Prof. Shahnaz Taing and Dr. Shazia Nisar
Subject Area: 
Health Sciences
Abstract: 

Background: Pregnancy has a profound effect on the thyroid gland and its function. Hypothyroidism complicates 0.3-0.7% of all pregnancies. Most common cause of hypothyroidism in pregnancy is Hashimoto’s thyroiditis. Women with thyroid autoimmunity are twice as likely to experience spontaneous miscarriages. Hence, there is a need to screen for subclinical hypothyroidism and thyroid autoimmunity in pregnancy, especially in women with a history of miscarriages. Objectives:(a) To assess prevalence of hypothyroidism in a hospital based sample of Kashmiri women with recurrent abortions and perinatal outcome after receiving treatment. (b) Is universal screening needed or not? Methodology: It was a prospective hospital based multiple unit study. Two groups were formulated, one group comprising of 100 pregnant women with a history of two or more recurrent abortions were labelled as case group while as another group comprising of 100 pregnant patients with one successful pregnancy were labelled as controls. Prevalence of subclinical hypothyroidism, thyroid auto immunity and maternal and fetal complications were analysed in the groups with appropriate statistical methods. Results: In our study the prevalence of subclinical hypothyroidism in case group with recurrent miscarriage was 27%. Thyroid autoimmunity was present in 31% of cases while as in controls it was 18 %, p-value statistically significant (0.033). Also mean TSH of cases and control groups were not significant (0.893). Complications between cases and controls were statistically not significant after receiving treatment. However postdatism was statistically significant (p value 0.024). Another subgroup was created within case group labelled TPO positive and TPO negative groups, TPO positive were 31 in number, while 61 were TPO negative. Statistical comparison was drawn between these two groups. The mean TSH in TPO positive group and TPO negative group was statistically significant (p value 0.001). With respect to complications between TPO positive and TPO negative groups, there was no statistical significance. However, IUGR was statistically significant with p value of 0.002. Hypothyroidism was statistically significant with 27 in TPO positive and none in TPO negative, p value 0.001. Conclusion: The prevalence of subclinical hypothyroidism and thyroid autoimmunity was higher in pregnant women with a history of recurrent abortion compared with a healthy pregnant control population. Following L-T4 treatment, there was no difference in the prevalence of miscarriage between hypothyroid and euthyroid individuals in TPO positive women. All euthyroid women with thyroid autoimmunity should be treated with LT4 to achieve a favourable maternal and perinatal outcome.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran