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Prevalence and spectrum of opportunstic fungal infections among post Covid patients

Author:

Dr. Pralitha Madhuri, G., Dr. Rajaram, G. Dr. Srinivasa Rao, CH.

Subject Area:

Health Sciences

Abstract:

Opportunistic fungal infections (OFI) following respiratory viral infections has been recognized since 1918 Influenza pandemic. Major risk factors for OFI include neutropenia, hematological malignancies, transplantation, prolonged treatment with corticosteroids, diabetes, prolonged stay in ICU, major surgery. POST COVID 19 associated fungal infections like candidiasis Mucormycosis, Aspergillosis are on the rise during the second spike of corona, as they exihibit immunosuppression with decrease in CD4+ and CD8+ T cells. CORONA is associated with an increase in pro inflammatory markers such as IL1,IL-6 TNF alpha which predisposes to bacterial and fungal infections. CORONA in diabetic patient leads to immune dysregulation and with steroid usage leads to immunosuppression and high risk for OFI.

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