Herbal as health solution has regained its popularity because many studies have substantiated it. A Qualitative analysis was conducted through standardized accepted laboratory technique for screening and study of bioactive compound present in Loranthus parasiticus , a hemiparasitic taxa collected from South west Bengal, India. Qualitative phytochemical analysis of this plant confirmed the presence of phytochemicals such as: alkaloids, flavonoids, tannins, terpenoids, reducing sugars, carbohydrates and cardiac glycosides in aqueous extract. This study deals with the significance of these phytochemicals with special reference to their use in traditional medicinal system. Initial study has indicated the significant anti-microbial activity of the leaf extracts of Loranthus parasiticus against Bacillus subtilis, Klebsella pneumoniae, Vibrio cholerae and Escherichia coli.