CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Possible risk factors of progression to overt disease among individuals with latent tuberculosis infection in Sudan

Author: 
Amani O. Shakak, Eltahir A. G. Khalil, Ahmed M. Musa, Kawthar A. M. Salih, AbdElgadir A. Bashir, Ala H. Ahmed, FathElrahman M. Idris and Ahmed M. Elhassan
Subject Area: 
Health Sciences
Abstract: 

Latent TB infections (LTBI) constitute a pool fornew TB cases, ~5% of LTBI individuals progress to overt disease during their lifetime. Simple and cheap progression risk factors are needed to triage individuals for treatment. In aprospective case control study and following informed consent, apparently healthy 98 household contacts (HHCs) and 186 community contacts (CCs) were enrolled. Tuberculin skin test (TST), whole blood stimulation/IFN-γ release assays and IL-4/IL-4δ2 mRNA copies were studied. Two hundred eighty-four volunteers were enrolled, five percent (5/98) of HHCs developed smear positive pulmonary TB compared to none in the CCs (p=0.004). The mean TST induration of the newly diagnosed TB patients was 16±2 mm at recruitment and the lapse of time to development of overt disease was 12±10 months. The majority of newly diagnosed TB patients had IFN-γ production levels below the cutoff level for LBTI diagnosis. A third of the HHCs and CCs had high IFN-γ levels, but none developed overt disease. The ratio of IL-4/IL-4δ2 mRNA copies in the newly diagnosed TB patients was significantly higher than that of the CCs (p0.0002). TST induration of ≥15was identified as a suitable simple and cheap test to triage individuals with LBTI for treatment.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran