Background: The aim of this study was to assess the knowledge, attitude, and practice regarding early childhood caries (ECC) among pediatricians in Amritsar city. Material & Method: A systematic random study was conducted among 120 pediatricians in Amritsar city by using a self administered questionnaire. Results: Pediatricians lacked ECC-related knowledge. Most of them were unaware of the first dental visit. All pediatricians agreed that both medical and dental professionals together are responsible for infant oral healthcare and they should work together to appropriately educate and train themselves to be able to provide risk assessment and to provide preventive oral health services.