This is a retrospective study from January 2017 to December 2017 at the Department of Neuropsychiatry, University Hospital Joseph Raseta Befelatanana Antananarivo, Madagascar. This study aims to describe the clinical aspects after waking up of ethyl coma. We included all woken-up comas after resuscitation with neuropsychiatric symptoms. But excluded, unknown patients, incomplete files or released against medical advice. We collected 123 patients, one hundred and ten (89%) are male versus thirteen (11%) female. The middle age is 37 years old. Farmers and low education represent the majority of our patients. Seventy-six patients (61.79%) were married, thirty-three (26.83%) were single, and fourteen (11.38%) were divorced and widowed. The main neurological clinical manifestations were withdrawal syndrome (n = 90), seizure and status epilepticus (n = 60), Gayet Wernicke's encephalopathy (n = 22), korsakoff syndrome (n = 12), pellagous encephalopathy (n = 7), cerebellar syndrome (n = 30), alcoholic polyneuropathy (n = 40), optic neuropathy (n = 3), alcoholic dementia (n = 2). The Psychiatric manifestations were mainly depression (n = 16) and alcoholic psychosis (n = 7). At the end of this study, we can conclude that wakeful comatose patients often have serious neuropsychiatric complications that are still a problem of management.