The integrative review was the choice for the elaboration of this study, since it understands that this method allows the synthesis of completed researches and obtains conclusions from a studied phenomenon. This study aimed to identify nursing interventions described in the literature that contribute to the humanization of care to neonates in a Neonatal Intensive Care Unit (NICU). The criteria used to select the sample were: articles published in Portuguese, listed in the following databases: Latin American Literature in Health Sciences - LILACS, International Literature in Sciences of the Saide - Medline, Scientific Electronic Library Online - SCIELO and Google academic. The period of publication of the articles was not delimited during the search. The descriptors used were: Critical Care Nursing, Humanization of Care and Neonatology. For the sample, 6 articles were selected because they met the eligibility criteria. The results demonstrate that nursing actions related tohumanization in NICU should be based on the construction of individual care, integrality and in the respect for life.