The full 9 stepped cycle of proton conductance and the biosynthesis of purine base after partial, complete stop of proton, electron flows

Without ATP making bioenergetic reaction medium as “Donators + membrane - redox potentials three - state line system + O2 + АDP + Pi + H+ + nH + membrane space = (ATP + heat energy) + H2O + nH + matrix + CO2” where formed such very important macroergic compounds as ATP, ADP and powerful reducing agent as NADPH it is absolutely impossible the biosynthesis of purine base, therefore the biosynthesis of DNA and RNA molecules. In such way the 5-phosphoribosyl - alpha - pyrophosphate (PRPP) molecules, which have been synthesized with participation of ATP and CO2, ATP molecules formed within reaction mediums as “Donators + membrane - redox potentials three - state line system + O2 + АDP + Pi + H+ + nH + membrane space = (ATP + heat energy) + H2O + nH + matrix + CO2” owing to the clockwise normal flow of electrons and protons by including in the structure of inosine monophosphate (IMP) after conducting the corresponding reactions became the unseparable structural parts of purine base molecules, also DNA, RNA molecules. The disturbance and stop of ATP dependent biosynthesis of purine base molecules and DNA and RNA molecules have been lead to the death, reversible damage of cells.