CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Distribution of class d oxacillinases amongst third generation cephalosporin resistant nosocomial uropathogenic escherichia coli isolates, their phylogenetic background and clonal analysis

Author: 
Debojyoty Bandyopadhyay and Mandira Mukherjee
Subject Area: 
Life Sciences
Abstract: 

Wide diversity of β-lactamases causes resistance to third-generation cephalosporins (3GCs) in uropathogenic E. coli (UPEC) the frequently encountered nosocomial pathogen creating treatment complications. In the present study incidence of OXA type ß-lactamase in 3GC resistant UPEC was explored. Phylogenic background and genetic relatedness between the isolates was also analyzed. 40.5% E. coli resistant to 3GCs were isolated from 190 urine culture positive samples from hospitalized patients clinically diagnosed for urinary tract infection (UTI). Highest resistance was observed against non-β-lactams; ciprofloxacin(100%), levofloxacin(90%), cotrimoxazole(95%) and intermediate resistance against amikacin(55%). ESBL(44.15%) production and β-lactamase inhibitor resistance (BLIR;55.84%) was observed with varied imepenem(100%, 88.37%) susceptibility respectively. Multiple β-lactamases (OXA group I, II, III, TEM, CTX-M) were prevalent. Occurrence of OXA group I, III and TEM was highest amongst ESBL(44.1%) compared to BLIR(32.6%) isolates. OXA group I, II and III β-lactamases either alone or in combinations with other β-lactamases were carried on IncF type plasmid (IncFrepB, IncFIB). Majority of the UPEC belonged to B2(75.32%) and D(22.07%) and their ERIC-PCR profiles indicated genetic homogeneity. This study for the first time demonstrated high distribution of OXA group I and III in 3GC resistant nosocomial UPEC isolates of homogeneous genetic origin from the eastern region of India.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran