
Unicystic ameloblastoma is the benign, locally invasive odontogenic tumors which histologically shows typical ameloblastomatous epithelium lining part of the cyst cavity, with or without luminal and/or mural tumor growth. A case of symptomatic unicystic ameloblastoma in 16- year-old-female, who has treated by surgical decompression followed by enucleation in 2 stage surgery is presented. The present case report describes the clinical and radiological behaviors, its importance and complexity of a differential diagnosis and treatment protocol of lesions in the mandibular molar-ramus area in teenagers.