CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Utility of vegf, ki67, and glut-1 immunohistochemical markers in differentiating palmoplantar psoriasis from chronic eczematous lesions

Author: 
Fatemeh Montazer, Zahra Safaeii Naraghi, Pedram Mehryan and Dorna Motevalli
Subject Area: 
Health Sciences
Abstract: 

Background: Based on clinical and histomorphological study, differentiating Chronic Plaque Psoriasis from chronic eczematous lesions of palmoplantar region is a diagnostic challenge, however, it has some implications for the patient's management and prognosis. Aim: This study is designed to evaluate immunohistochemical markers for distinguishing psoriasis from eczema of palmoplantar region in patients referring to Razi Skin Hospital, Tehran, Iran. Materials and Methods: Comparative cross-sectional study was carried out at Razi Skin Hospital, Tehran, Iran. Immunohistochemical stains for VEGF, Ki67, and GLUT-1 were performed on 45 cases including 15 patients with palmoplantar psoriasis, 15 patients with palmoplantar eczematous lesions, and 15 patients with diagnosis of lichen planus as control group. Results: The expression of Ki-67 were not significantly different between psoriatic and eczematic lesions but it was more severe in patients with psoriasis. VEGF staining showed a higher vascular proliferation in psoriasis than in eczema and lichen planus. There was no significant difference between GLUT1 expression in 3 examined groups but most cases of psoriasis show diffuse distribution for GLUT1 staining compared with eczema and lichen planus, which mostly show discontinuous staining for GLUT1 marker. Conclusion: Our findings indicate that VEGF immunostaining shows a significantly more expressed vascular proliferation in patient with psoriatic lesions, and can be helpful as immune marker for differentiating palmoplantar psoriasis and eczema of this region.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran