CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Total antioxidant capacity and certain cytokines in patients with bladder Cancer

Author: 
Hind S. Jasim and Sajedah A. H. Khalil
Subject Area: 
Health Sciences
Abstract: 

Objectives: Bladder cancer (BC) is one of the most widespread cancers distressing men and women and thus has a philosophical impact on health care. An extensive variability in the occurrence of BC reflects its multifactorial with polygenic etiology. Antioxidants play an essential role in protection of the cells from oxidative damage. Antioxidant defense can be affected in cancer. TNF-α is one of the major mediators of inflammation and has been linked to all steps involved in tumor genesis, including cellular transformation, promotion, survival, proliferation, invasion, angiogenesis, and metastasis. Tumor cells secrete their own TNF-α in anticrime manner which further enhance the expression of other growth factors such as transforming growth factor (TGF). The aim of this study was to evaluate the serum total antioxidant capacity, TNF-α, TGF-β levels in patients with bladder cancer. Methods: fifty patients with bladder cancer and 20 controls were enrolled in the study. Serum TAC, TNF-α, TGF-β levels were determined. Findings: Serum TAC, TNF-α and TGF-β were significantly elevated in BC over that of the control (p = 0.0001). Data analysis according to the grade of the disease show a significant difference among high grade, low grade & control groups with significant differences in TAC, TNF-α and TGF-β levels between high and low grade groups (p<0.001). Conclusion: Our results suggest that increased TNF-α and TGF-β with decreased antioxidant levels may be, in part, play a role in the pathogenesis of bladder cancer and may help in diagnosis, treatment and follow up of bladder cancer patients in the future.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran