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T-2 mycotoxin induced toxicity: a review

Author:

Rachitha, P. and Farhath Khanum

Subject Area:

Life Sciences

Abstract:

T-2 toxin is a member of trichothecene mycotoxin. The major toxic effect of T-2 toxin is that it inhibit protein synthesis which is followed by a secondary disruption of DNA and RNA synthesis. T-2 toxin affects the actively first through skin and it causes heamatotoxicity, neurotoxicity, reproductive toxicity, genotoxicity and it can decrease antibody levels, immunoglobolines and certain other humoral factors. In addition, in this review article discussed about outbreaks of T-2 toxin and its biosynthesis, toxicokinetics regulatory matters related to its use as a potential warfare and treatment.

PDF file:

6759.pdf

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