The loss of dental elements is one of the main factors for the pneumatization of the maxillary sinus. The lack of bone crest dimensions in both height and width is an important indication for maxillary sinus lift surgery that aims at future oral rehabilitation. Case Report: A female patient, leucoderma, 41 years old, sought care at a postgraduate center and complained that she had no dental elements on the right side, claiming that she would like oral rehabilitation. After anamnesis, an accurate clinical examination and volumetric tomographic of the conical bundle, the pneumatization of the maxillary sinus was diagnosed and surgical intervention was required to lift it. Final Considerations: Maxillary sinus lift surgery using the lateral window technique with the use of L-PRF aides with the bovine matrix xenografts used has an easy surgical feasibility of material handling as well as allows better results for oral rehabilitation, besides allow a quick post surgical.