The competitive advantages that make and unmake the sectoral structure of Tunisian regional economies remain the same. Indeed, the sectoral structure of regional economies of Tunisia remain heavily dependent on competitive advantages that enabled their emergence, despite the upheavals and difficulties faced by some sectors in this area. Reliance on the cost of production factors remains important for the regions of the west and south, despite some areas that are beginning to emerge. This dependence has affected negatively the outbreak of entrepreneurial spirit in this environment with, for young people, a lack of known entrepreneurs on which they could take such models.