Acute paracetamol poisoning is a common cause of drug poisoning in both developed and developing countries. It leads to severe liver injury. N-acetylcysteine’s effectiveness (NAC), an antidote to paracetamol, usually depends on the time between ingestion and management. In the following case, we report a 5-year-old child who presented with acute hepatic encephalopathy after acute paracetamol intoxication and who progressed favorably despite NAC’s delayed administration.