A novel root Biomodifier containing Chlorhxidine and EDTA–an ESEM analysis

Objective: EDTA (Ethylenediamenetetracetic acid) and Chlorhexidineare potent chelating and bactericidal in nature. QMIX ® (Dentsply Tulsa Dental, USA) has been developed as a two in one single irrigation solution containing EDTA and Chlorhexid in and to be used after a final rinse post bleach. Due to the properties of its composition, QMIX has the potential to modify as well as disinfect the intracanal root surface. Thus the aim of this in vitro study was to evaluate the efficacy of QMIX ® on the removal of smear layer from periodontally affected root surfaces. Materials and Methods: 30 longitudinally sectioned specimens from 15 freshly extracted teeth diagnosed with advanced periodontal disease were divided into two groups. In group A and B, the root surfaces were scaled and irrigated using normal saline and with QMIX ® respectively. All specimens were prepared for ESEM (Environmental scanning electron microscope) and scored according to the presence of smear layer. Results: QMIX® significantly increased smear layer removal as compared to the associated control group, in which only saline was used Conclusion: QMIX® increased the removal of the smear layer from periodontally affected root surfaces. Thus use of QMIX can be of therapeutic value and may be suggested as a root conditioner on diseased root surfaces. Clinical Relevance: A novel Agent with known chelating and bactericidal properties to be used for root biomodification on diseased root surfaces in order to facilitate attachment of periodontal fibers and aid in periodontal regeneration.