Novel amnion allograft in the treatment of gingival recession compared with coronally advanced flap

Aims: To demonstrate the viability of amniotic membrane for the treatment of mucogingival defects (shallow-to-moderate Gingival recession defects). Methods: The aim of this study was to record the use of processed dehydrated allograft amnion in the treatment of 20 shallow-to moderate recession defects defined as ≤3 mm of recession. Patients were randomly divided into 2 groups to receive either Amniotic membrane graft with coronally advanced flap Group-1 or Coronally advanced flap Group-2 and followed up for a period of 6 months. Results: The results were statistically analysed using unpaired t test. The mean recession depth at baseline in both the groups was 2.75mm±0.78mm. 24 weeks postoperatively the mean recession depth was 0.15mm±0.36mm and group 2 it was 0.35mm±0.48mm. The difference between group 1 and 2 was not statistically significant in any of the occasions as analysed with independent samples t test. However, better root coverage was achieved in group 1 when compared to group 2 at 24 weeks postoperatively as compared with values at baseline. Conclusion: Based on the data collected in this study, processed dehydrated amnion may provide an effective alternative to autograft tissue in the treatment of shallow-to-moderate Miller Class I and II recession defects.