The use of rubber dam is considered as the standard of care by professional organizations. The role of microorganisms in causing root canal infection is well known and the importance of eliminating them from the root canal system for successful root canal treatment. The use of rubber dam provides absolute dryness of the field, better control of cross-infection, prevents soft tissue contact of chemicals, and improves treatment efficiency. However, recently by the introduction of many newer variations, its use in endodontics has been made easy. The purpose of this paper is to review the advances in rubber dam materials and discuss their possibilities to use in endodontics.