Moya moya disease

MoyaMoya disease was discovered in 1957 by Japanese surgeon (Takeuchi and shimizu). It is a rare progressive cerebrovascular disorder that affects the brain blood vessels and the internal carotid arteries become narrowed or blocked. Its most commonly occur in paediatrics and adults, It is a ideopathic vascular disorder of intracranial arteries, the cause is unknown and sometimes it may be due to DNA mutation, the incidence of this disease is high in East Asia and more common in female at birth as compared to male at birth ,in children’s usually occurs between the age group of 5to10 years while in adults occur between the age of 30 to 50 years and with the symptoms of facial asymmetry,seizure, involuntarymovement and also experience with the symptoms of ischemic attack and intracranial bleeding. Most common symptoms in paediatric are weakness of extremities, sensory disturbance and headache. It can be diagnosed by MRI, Cerebral angiogram,CT,Tran’s cranial Doppler ultrasound and it can be managed with the Revascularization surgery, vasodilator, antiplatelet, antifibrolytic and anticonvulsants drugs.