Background: Currently, laparoscopic appendectomy is widely practiced for the management of acute appendicitis. It is not clear whether open or laparoscopic appendectomy is more appropriate. Aim: Our aim is to compare the safety and advantages of laparoscopic versus open appendectomy. Methods: 120 patients were analyzed, out of which 60 patients underwent laparoscopic appendectomy (LA) and 60 patients underwent open appendectomy (OA). Comparison was based on length of hospital stay, operating time, post operative morbidity, requirement of post operative analgesia as well as resumption of regular diet. Results: the median length of stay was shorter after LA which was 3 days where as in OA it was 5 days (P < 0.05). The operative time was shortened (OA:25 minutes (median), LA 30 minutes (median) with (P = 0.29)) for patients undergoining open appendectomy compared to laparoscopic appendectomy which is not significant. The rate of wound infection and complication (LA 3%, OA 8% , P <0.05), was significantly lower in patients undergoing LA. There was no mortality. Conclusion: LA is safe and superior to OA with respect to early discharge, lesser post operative pain, decreased wound infection, early return to work, lesser hospital stay and better cosmetic results.