Burn injuries are of major concern with respect to morbidity and mortality.It isthe leading cause of death among children worldwide. Burn damages cell membrane, causes loss of cell integrity and membrane permeability which brings major changes in serum electrolytes. Liver, kidney and pancreas are among the most vulnerable organs in burn trauma, markers of which help to assess the pattern and severity of injury. Hepatic changes are constantly reported in burns. This includes plasma proteins, acute phase reactants, various enzymes and coagulation factors. These parameters suggest the degree of severity, risk involved and prognosis. This is an effort to put all these hepatic markers together.