A series of 1,2,4-triazole,2-aryllidine hydrazono benzoazole and 3-chloro-2-azetidinone derivatives were synthesized via reactions with different reagents. Reactions were carried out by green synthesis method such as microwave technique andgreen catalysts.The structure of the prepared compounds have been characterized on the basis of their elemental analysis and spectral data.Some of the new compounds were screened for their antimicrobial activity.