Objective: The purpose of this study is to evaluate functional outcome of open reduction and internal fixation with proximal humeral internal locking system (PHILOS) for proximal humerus fractures. Method: Functional outcomes of 11 men and 17 women aged 27 to 76(mean, 53.21) years who underwent Philos plate fixation for proximal humeral fractures by deltopectoral approach were reviewed retro prospectively. 18 patients were in the age group of <60 years and 10 patients in the age group of >60 years. According to Neer classification system, 5, 9 and 14 patients had 2-part, 3-part, and 4-part fractures, respectively. Functional evaluation of the shoulder was done using Constant-Murley score. Results: Patients were followed up for 12 to 18 (mean 15) months. All fractures united clinically and radiologically. The mean time for radiological union was 13 weeks (range 10-18 weeks). At the final follow-up the mean Constant-Murley score was 72 (range35-90). The results were excellent in 8 patients, good in 15 patients, fair in 3 patients and poor in 2 patients. During the follow-up, 2 cases of malreduction, two cases of subacromial impingement and one case of infection were noted. No cases of AVN, hardware failure, locking screw loosening or nonunion were noted. Conclusion: Philos plate fixation provided stable fixation and allowed early range-of-motion exercises.