The present study is an attempt to investigate the action of supplementary feed on morphometry and digestive tract enzymes of Catla catla. Juveniles of healthy fish, Catla catla were collected from Fish farm. Fish artificial nutrients were clearly mixed in right proportion and allowed to dry for 24 hrs. Using a standard scale and measuring board, the morphometric characters were analysed. Digestive enzymes such as amylase, protease, invertase, lipase and maltase in both control and treated fish samples were tested adopting the standard methods. The present study showed high digestive enzyme activity in control compared to fishes exposed to all other treatment. Enzyme activity of control fish showed in the following order Protease > Lipase > amylase > Maltase >Invertase. On the other hand, amylase activity of tank C fish sample was increased 50% compared to control tank fish sample. Lipase activity is slightly higher in stomach and mid – gut region of control fish sample, but no activity in the foregut and hindgut sample (all group). Combination food supplement such as soya meal, groundnut cake and wheat show remarkable changes in fish Morphometry and digestive tract enzymes. In this combination of food supplement to be improve growth of fish as well as their routine physiological metabolism.