Purpose: Chronic periodontitis (CP), the commonest type of periodontal disease caused progressive loss of attachment and bone loss. It is closely related to several systemic diseases, such as diabetes and cardiovascular disease. The link between periodontal disease and chronic kidney disease(CKD) may be due to infection and inflammation. The periodontal inflammatory state may increases the chronic inflammation present in CKD, thus decreasing renal function. Periodontal therapy may reduce inflammation and improves endothelial function. Materials and Methods: Fifty one CP patients (Age 35- 60 years) was selected. Categorized into group I and groups II. Group I was test group (TG) included twenty five patients and group II was control group (CG) included twenty six patients. Scaling and root planing (SRP) was done in test group only. Serum renal function and clinical parameters were checked at baseline and one month after SRP. Results: After comparison of the clinical parameter and renal function markers at baseline there is no statistical difference among TG (p= 0.102). Before and after Comparison (baseline and 1 month) in TG, the clinical and renal function markers were statistically significant (p < 0.001). Conclusion: In the study there is significant improvement in periodontal parameter, which shows periodontal improvement, also serum creatinine, urea and bilurubin levels showed improvement after SRP.
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