This study was designed to investigate sense relations of lexemes in Macha Dialect of the Oromo Language through the application of linguistic knowledge. It was set to identify the different horizontal and vertical sense relations in the dialect and to describe them systematically. Qualitative method was used to achieve the objectives of the study, and text analysis was employed in the discussions of the findings. The sense relations predominantly used in the dialect are antonymy, synonymy, hyponymy, homonymy, polysemy, member-collection, meronymy, portion-mass and metonymy. Some of these relations are further categorized into parcels of smaller sense relations.