Background: Coronavirus disease 2019 (abbreviated “COVID-19”) is an emerging respiratory disease that is caused by a novel coronavirus. The disease is highly infectious, and its main clinical symptoms include fever, dry cough, fatigue, myalgia, and dyspnea. To guarantee the final success, people's adherence to these control measures are essential, which is largely affected by their knowledge, attitudes, and practices towards COVID- 19. Objective: This study aims to investigate the knowledge about public’s awareness about COVID-19 during the pandemic spike. Method: The method used is a survey based questionnaire. Result: The mean COVID-19 knowledge score was 10.8 (SD: 1.6, range: 0-12), suggesting an overall 90% correct rate on this knowledge test. Conclusion: In summary, our findings suggest that Indian residents of a relatively high level of socioeconomic status, have had good knowledge, optimistic attitudes, and appropriate practices towards COVID-19 during the rapid rise period of the COVID-19 outbreak. Hopefully, under the combined efforts of Indian authorities and all Indian residents, India surely will win the battle against COVID-19 in the near future.