Senegal, due to its geographical position, has a great diversity of plant species that can contribute to food security. However, they tend to disappear due to changes in diet. As a result, there is an urgent need to know these species and the knowledge associated with them. This study contributes to the knowledge of neglected and underutilized species in Senegal. More specifically, it aims to know the species of the genus Nymphaea used in the low and deltas of the Senegal River and to determine the various uses and uses of the species. This is a survey of 340 people in 17 villages in the delta and lower Senegal River. It allowed to see two species used: Nymphaea lotus and Nymphaea micrantha. The only organs of this species used are the seeds and bulbs. The diversity of uses shows their importance in the region. The Informant Consensus Factor (FCI) greater than 0.90 reveals in the assembly a high-level agreement of our informants on the use of these plants in food and pharmacopoeia. However more and more they are abandoned for reasons related to the insalubrity of the places of harvests and the difficulties met during the harvest and the transformation Faced with this situation, it is important today to continue the investigations in the sense of valorization.