Aim: The purpose of the study was to clinically evaluate and compare the efficacy of human fibrin sealant (Tisseel®) with non-absorbable surgical suture in the treatment of localized gingival recession. Methods: The study population consisted of 30 identical gingival recession defects. The selected gingival recession sites were randomly assigned either to 1) Control site A(lateral pedicle flap with suture) or 2) Test site B(lateral pedicle flap with Tisseel®). The clinical parameters plaque index, gingival index, recession width, width of keratinizedgingiva, and recession depth were recorded at baseline 7, 30 day postoperatively. Clinical attachment level were recorded only at baseline and 1 months post-operatively. Results: At 1 month the recession width and depth were reduced in both the groups (Control site A & Test site B) with mean root coverage of 34% and 47%respectively.On intergroup comparison, the mean difference in different clinical parameters was statistically not significant. Conclusion: Both groups showed the potential of achieving root coverage; however on comparison between the two groups, the results obtained of lateral pedicle with Tisseel group were slightly better although statistically not significant.
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