Comparative evaluation of effect of Papain and Bromelain containing toothpaste and commercially available flouridated toothpaste

A randomized, double blind, pilot clinical study was performed to compare the effectiveness of a herbal – based test toothpaste on reduction of existing plaque, gingivitis and extrinsic dental stains with a normal commercially available fluoridated toothpaste, over six weeks. 40 subjects were instructed to brush twice daily with the assigned toothpaste (either of the toothpaste) and toothbrush using modified bass method of brushing and refrain from other unassigned forms of oral hygiene aids. No prophylaxis was undertaken prior to commencement of the study. Subjects were assessed at baseline, and 6 weeks using plaque index, gingival index and Macpherson et al. modification of Lobene stain index and bleeding index. Immediately after completion of six weeks, subjects received a professional prophylaxis. The present study concludes there is significant reduction in the dental plaque accumulation and thus significantly reducing the chances of gingivitis in the subjects which used toothpaste having papain and bromelin. Also these natural extracts in the toothpaste showed significant reduction in stains after 6 weeks when compared to a regular fluoridated toothpaste.