Cleidocranial dysplasia is a congenital anomaly that is clinically characterized by complete defect or hypoplasia of the clavicle and abnormal ossification of the skull. In the maxillofacial region, it has various abnormalities such as reversed occlusion with hypoplastic midface, persistence of deciduous teeth with delayed eruption of permanent teeth, supernumerary teeth and malalignment. A case of cleidocranial dysplasia in a 17-year-old female visited our hospital. After the preoperative orthodontic treatment for 2 ½ years, Le Fort I osteotomy and Bilateral sagittal split osteotomy for the hypogrowth of the maxilla was performed to advance it anteriorly and set back the mandible. Her midface appearance and the occlusion were remarkably improved after the surgery.