Mesenteric panniculitis is a rare, benign and chronic fibrosing inflammatory disease that affects the adipose tissue of the mesentery of the small intestine and colon. The specific etiology of the disease is unknown. The diagnosis is suggested by computed tomography and is usually confirmed by surgical biopsies. Treatment is empirical and based on a few selected drugs. Surgical resection is sometimes attempted for definitive therapy, although the surgical approach is often limited. We report a 44-year-old male with a past medical history of hypertension, and alcohol abuse presented with complaints of nausea and abdominal pain. CT scan of the abdomen was done which showed fat stranding around mesentery, representing mesenteric panniculitis.