Background: Mucoepidermoid carcinoma (MEC) is the most common malignant neoplasm of the major salivary glands, accounting for 15.5% of all cases, benign and malignant. Mucoepidermoid carcinoma is the most frequent primary salivary malignancy, followed by adenoid cystic and acinic cell carcinoma. Case report: This case corresponds 40 years-old male patient who reported to the outpatient department of RMCH Bareilly, UP with the chief complaints of painless swelling with pus discharge on the left preauricular region of the face since 2 years. The mass was associated with wound and pus discharge and lymphodenopathy. MRI neck reveals relatively well defined oval lobulated mass lesion involving the left parotid. Core biopsy of the lesion revealed impression of MEC. Outcome: Parotidectomy procedure was done involving both superficial and deep lobes taking care not to injure the facial nerve. The histological picture confirmed that the tumour was MEC of parotid gland. Discussion: MEC of the parotid gland clinically manifest as an asymptomatic swelling. A low and intermediate grade of tumors often undergoes primary surgical excision and a High-grade tumor includes surgical excision with wide margins followed by radiotherapy. Prognosis depends on three main factors: clinical stage, histological grade and treatment. Distant MEC metastases relate to a poor prognosis. The survival rate for patients with distant metastases is 2.3 - 2.6 years.
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