A case of acute respiratory distress syndrome following treatment of Babesiosis was reported in a 2 year old male Maltese terrier. The patient was admitted to the clinic following a history of anorexia and dullness with preferred recumbence. Main presenting signs on admission were severe pallor, prolonged clotting time, and dyspnoea, lethargy. Blood smears obtained from the ear revealed multiple Babesia parasites, severe regenerative anemia, neutrophillia and monocytosis. After meticulous clinical therapy for 5 days patient was discharged having become more active and with improved appetite. Within 24 hours of discharging form the clinic patient developed sudden dyspnoea. Patient went into respiratory shock within 2 hours of the onset of dyspnoea the patient died before arrival at the clinic.