Oral submucous fibrosis is a chronic inflammatory disease that results in progressive juxtaepithelial fibrosis of the oral soft tissues that can cause increasing difficulty in chewing, swallowing, speaking, and mouth opening. Many treatment regimens for oral submucous fibrosis have been proposed to alleviate the signs and symptoms of the disorder. In severe cases, surgical intervention is the only treatment modality, but relapse is a major problem. Even after 6 decades of its description as a separate entity, no concrete treatment is available due to its multi-modal pathogenesis. Thus, adding to the morbidity associated with it. Current article is an attempt to compile the available treatment aids, their current status and future perspectives, so as to aid early intervention of the disease.