Advancements In Regenerative Endodontics: Platelet-Rich Plasma (Prp) And Platelet-Rich Fibrin (Prf)

Pulp vitality is very important for tooth viability, as it provides nutrition and act as alarm to detect pathogenic stimuli. Regenerative endodontic procedures aim at regeneration of pulp and dentin of the affected teeth. The aim of this review is to add a new prospect in regenerative endodontic therapy by using platelet-rich plasma (PRP) and platelet-rich fibrin (PRF). PRP and PRF have an intimate assembly of cytokines, glycan chains and structural glycoproteins which are enmeshed in polymerized fibrin network, and have the potential to accelerate soft and hard tissue healing. Thus this review is intended to add light on the various prospects of PRP and PRF and clinical insights to regenerative endodontics.