Acute pancreatitis in children; incidence and complications; systematic review

Acute pancreatitis in children is a costly and increasingly recognized disease. As in grownups, the occurrence of intense pancreatitis in children likewise appears to be growing. Several studies have actually documented an increase throughout the past 10 to 15 years. The aim of this systematic review study was to review complications and incidence of acute pancreatitis in children, also we aimed to discuss the etiology regarding AP all these are based on evidence of human population studies from the pediatrics literature. We performed an electronic search of MEDLINE, EMBASE, and SciELO databases. These databases were searched for eligible studies discussing the complications, etiology and epidemiology of acute pancreatitis in children population. Our search had no limit period of studies publication, therefore, we searched through December 2016 Relevant references and historical quotes, as well as extremely important studies within the context of the review were analyzed in the same way, regardless of the publication dates. The incidence of intense pancreatitis in children has actually been increasing for the past 2 years, most likely as a result of multifactorial causes. AP is a disease of great significance in children, due to its tough medical diagnosis and severity of symptoms and associated complications; besides, it has a significantly higher occurrence because of a growing suspicion and better knowledge of its clinical qualities. The main causes of AP in children are biliary disease and medication, however as much as 1/3 of patients might not have a defined etiology at diagnosis. Issues of severe pancreatitis in children are sterilized and infected collections, fistulas, and vascular complications.