CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Evaluation of the dosimetric differences in esophagitis induced from radiotherapy of lung cancer patients using three different radiation techniques

Author: 
Rui He, M.S., Elgenaid Hamadain, Hamed Benghuzzi, Satya Packianathan, Madhava R. Kanakamedala, Michelle Tucci, Robert M. Allbright, Sophy H. Mangana, Srinivasan Vijayakumar and Claus Chunli Yang
Subject Area: 
Health Sciences
Abstract: 

Objective: To evaluate the dosimetric differences in esophagitis induced from radiotherapy using three radiation techniques of lung cancer patients: “Low-Modulated” Intensity Modulated Radiation Therapy (LM-IMRT), Stereotactic Body Radiation Therapy (SBRT) and Three Dimensional Conformal Radiation Therapy (3DCRT). Methods and Materials: In this retrospective study, treatment charts of 243 lung cancer patients treated with radiation therapy or combined with chemotherapy from year 2014 to 2017 at University of Mississippi Medical Center (UMMC) Radiation Oncology were reviewed. The dosimetric parameters such as mean esophagus dose (MED), Dmax, Dmin, V5, V10, V15, V20, V30, V40, V50, and V60from three treatment techniques are collected from the Pinnacle treatment planning system. One way ANOVA method was used to compare the dosimetric parameters, and Tukey multiple comparison tests were used for pairwise comparisons of the three treatment techniques. Results: There were significant difference indosimetric parameters between SBRT and LM-IMRT, and between SBRT and 3DCRT. There were no significant difference between LM-IMRT and 3DCRT for mean esophagus dose, V5, V10, V15, and V20, but there were significant difference for V30 and V40 for treatment prescription of 3DCRT at 37.5Gy in 15 fractions(or 30 Gy in 10 fractions) and LM-IMRT at 60Gy in 30 fractions (or 59.4 Gy in 33 fractions) daily. However, after rescaling the prescription of the 3DCRT to the same level of LM-IMRT at 60Gy in 30 fractions daily, dosimetric difference of esophagus between 3DCRT and LM-IMRT turned out to be statistically significant (p<0.05). Conclusions: The result of this study suggests that the Low-Modulated IMRT was superior compared to the 3DCRT technique in sparing the esophagus. Additionally, it is important to rescale the dose prescription to have apple to apple treatment technique comparison regarding the dosimetric parameters of esophagus from clinical application point of view. All treatment data for this research is from the single institute, therefore the variety of volumetric metrics of the esophagus from the different institute’s published data are avoided. Findings from this study can help clinicians in making decisions about which treatment technique to choose and how dosimetric parameters can be optimized to avoid potential complication in esophagus.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran