Evaluation And Comparison Of Anticancer Activity Of Herbomineral Complex

Background: Cancer is a bubonic plague to mankind for which presently, there is no cure Chemopreventive plant compounds such as catechin, curcumin affect all phases of the cancer process, i.e., tumor initiation, promotion and progression. But major drawback of these phenolic compound is their poor bioavailability Objective: Literature resources reveled that formation of complex of these phenolic compound with mineral will increase Bioavailability and free radical scavenging activity: Which stimulate our interest to form herbomineral complex and evaluate its effect on free radical scavenging and anticancer activity Material and Method: Herbomineral complex was formed by the process of chelation Phenolic compounds such as Catechin, Curcumin and polyphenols from Trigonella foenum graecum extract chelate the divalent metal ions Zn2+in weakly acidic aqueous solution. Formed complex was screened for anticancer activity on human nesopharyngeal cell line kB. Herbomineral complex of catechin and Trigonella foenum graecum extract showed potent anticancer activity.In the present study an attempt was also made to prove the therapeutic effect of herbomineral complexes of these drug