Effects of salvia officinalis l. (SAGE) on cognitive impairment in saudi aging people

Background and Aim: Elderly people are susceptible to cognitive impairment making them a particularly vulnerable group. The number of older people had cognitive impairment and dementia is increasing worldwide. Salvia officinalis (Sage) is a plant in the family of Labiatae. It contains a large array of active compounds that may enhance cognitive activity and protect against neurodegenerative diseases. This study aimed to assess the effect of the orally received sage tea extract for 4 weeks on improving the cognitive performance in elderly people. Methodology: Cross-sectional intervention study was conducted, one hundred participants 47 males and 53 females (aged 60 and older) received of S. officinalis (tea bag contain 2.5g), participate were received 2 cup/day for 4 weeks. Cognitive performance measured was assessed by the change in The Mini Mental State Examination (MMSE) score before and after received sage tea. Results: The mean age to all participants was 70.16±7.05. The cognitive performance was improve after received S. officinalis, there was a statistical significant difference (p< 0.001) for the MMSE score in both gander before and after one month of receiving sage with total score (22.57 and 25.25, respectively). Conclusion: Salvia officinalisis has potential health benefits; it improved cognitive performance for elderly participants. Further investigation is essential to help in elucidation the potential of this commonly ingested herb to enhance cognitive health and wellbeing.