Assessment of liver function tests in benzen station workers in khartoum State- Sudan

Background: Human in contact with petroleum products always in regular life needs as they are parts of many materials on consumption needs, the more affected individuals are those in direct contact with these products are individuals in work positions make easy direct exposure, as workers in petrol stations, petrol products enter the body though breathing from air; swallow in water, food, or through touching. Most components can enter the blood stream rapidly when inhaled. Liver one of the organs exposure to patrol components can lead to its damage which can be manifested in different patterns. Objectives: the aim of this study was to assess the liver function tests in benzene stations workers in Khartoum state- Sudan. Results: The results of the study revealed significant difference in serum Aspartate Amino Transferase (AST) and Alanine Amino Transferase (ALT) in case group as compared with control group with mean of (30.3) IU/L, (22.3) IU/L and (24.3) IU/l, (17.6) IU/L with (P.Value 0.001, 0.01) respectively. On other biochemical parameter there was no significant variation between case and control group (P.Value >0.05). Conclusions: There were no obvious effects on LFT in most of parameters, but LFT should be assessed with the time of work and an end point for such work should be kept in employment rules, to prevent irreversible damage in gas worker health status.