Seroprevalence of herpes simplex virus type- 1 pre- marital women in al-khalis city

Background: Herpes simplex virus type 1 (HSV-1) infection is a common viral illness, which classically causes oro-labial herpes (cold sores), becuase the virus are transmitted by contact with an infected area of the skin during re-activations of the virus Objective: To determined the seropositivity and determinants of serum IgG &IgM antibody against HSV-1 among pre –marital women in khalis city. Materials and Methods: Ninety one pre-Marital women were chosen from those attending the akhalis hospital in Khalis city - Diyala province, during the period from 1st December /2014 till 30th February 2015. The age range between (15-45) years. Anti- herpes simplex virus type 1 IgM and IgG antibodies were assayed by Enzyme linked immunosorbant assay technique. (ELISA) The result showed that 78 (85.7%) women had the antibody immunoglobulin (IgG), and nine (9.89%) women had IgM. The highest ratio of semple herpes virus type one for IgG and IgM were found in the age group 15-20 years. The results revealed that the highest titer of SHV1- IgG from rural areas (14.28) and 50(89.28) for IgM. Most of SHV1- IgM had medium eductional (95) and showed significant result to education Conclusion: Low prevalence rate of HSV-1 seropositivity was appeared among pre-Maritalwomen in studies area. However, it's necessary to focus on the women that demonstrated susceptibility for herpes simplex virus type 1 infection.